PEPperCHIP® Coronavirus SARS-CoV-2 Proteome Microarray
PEPperPRINT has developed a peptide microarray against the genome of the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2, previously 2019-nCoV) in response to the COVID-19 pandemic that was discovered late 2019.
PEPperCHIP® Coronavirus SARS-CoV-2 Proteome Microarray is derived from the published genome of the virus isolate Wuhan-Hu-1 (GenBank: MN908947.3). This microarray contains the whole proteome of the virus as 4883 partially overlapping peptides (printed in duplicates for a total of 9766 spots).
The microarray is effective for purposes such as:
➤ identify, profile, and compare specific IgG and IgM antibody responses in patient or animal sera
➤ screen viral antigens to find and characterize immunodominant epitopes
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Example Usage – Antibody Fingerprinting
The entire Coronavirus SARS-CoV-2 viral proteome is translated into overlapping peptides and printed onto glass slides. Patient sera is incubated on the chip and antibodies present in the sample bind to epitopes recognized within individual peptides. The resulting response profile may be compared across different samples to monitor B-cell responses over time, or to determine immunodominant epitopes that may be further validated as potential disease-specific biomarkers.
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|PEPperCHIP® Coronavirus SARS-CoV-2 Proteome Microarray||EXCEL|
|Microarray Content: Whole proteome of Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1 (GenBank: MN908947.3)
Peptide Length/Overlap: 15 amino acids/ 13 amino acids
Number of Peptides/Spots: 4,883 / 9,766
Compatible With: PPC.004.001 3/1 well PEPperCHIP® Incubation Tray
Please contact us for any inquiries, questions, or information requests.
Tokyo Future Style, Inc.