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BioLab Assays Ltd. is a dynamic life-science company that develops, manufactures and sells innovative and original ready-to-use ELISA (enzyme-linked immunosorbent assay) kits. Their portfolio includes solid phase 96-well ELIS designed for quantitative measurement of cytokines, acute reactant proteins or chemokines, and optimalised for serum, plasma, urine, saliva or CSF samples.

BioLab Assays also provides custom immunoassay development and contract manufacturing services to the diagnostic and research industry. They have over 20 years of experience in the research, development and production of ELISA kits and developed special formula for blocking, dilution and stabilizing buffers to provide a smooth and cost effective process for commercialization of immunoassay products.

• Human Monomeric CRP ELISA
• Research Areas
• Product List
• References

Human Monomeric CRP ELISAfor Quantitative Measurement of Monomeric CRP

• Human Monomeric CRP ELISA quantitatively measures monomeric CRP (mCRP) without cross-reactivity with pentameric CRP (pCRP).
• mCRP that is formed by dissociation of pCRP shows strong pro-inflammatory effects.
• There are studies on involvement of mCRP in pathogenesis of Alzheimer’s diseases, cardiovascular diseases, and autoimmune diseases.

Product information

Cat. No.

BA1026

Product Name

Human Monomeric CRP ELISA

Sandwich ELISA

Capture MAb specific to mCRP

Size

96 wells

Sample type

serum, plasma

Measuring range

1.25 – 80 ng/ml

Typical mCRP values

Clinical area	Serum mCRP range (median)
Individuals with hsCRP within 1-5mg/L	1.2 – 4.8 ng/ml (median 2.6 ng/ml)
Individuals with pancreatic cancer	18.3 – 73.9 ng/ml (median 36.5 ng/ml)
Individuals with bacterial infection, CRP over 50mg/L	24.1 – 98.3 ng/ml (median 47.7 ng/ml)

References

• Monomeric CRP – A KEY MOLECULE DRIVING DEVELOPMENT OF ALZHEIMER’S DISEASE?
• Monomeric CRP – A NEW PLAYER IN EVALUATION OF CARDIOVASCULAR RISK?

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Research Areas

Energy metabolism

Laboratory markers crosslinking obesity, insulin resistance, diabetes, high blood pressure and impaired lipid metabolism.

Retinol-Binding Protein 4 (RBP4), Epidermal FABP (EFABP, FABP5), Liver FABP (LFABP, FABP1), Galectin-3

Kidney disease

Acute kidney injury and chronic kidney disease markers.

KIM-1, FGF-23,Galectin-3

Lung disease

Markers of bone formation and resorption. Rheumatoid arthritis and osteoarthritis.

Surfactant Protein A (SP-A), KL-6, Galectin-3

Bone metabolism

Markers of bone formation and resorption. Rheumatoid arthritis and osteoarthritis.

Vitamin D Binding Protein, sRANKL, Sclerostin, Osteopontin

Animal studies

Veterinary care and preclinical testing.

Rat TSH

Miscellaneous

Infection, immunity, reproduction and endocrinology, oxidative stress.

Monomeric C-reactive protein, Anti-Mullerian Hormone (AMH, MIS), MMP-3, MMP-9, Alpha-Fetoprotein (AFP), D-dimer, suPAR, Serum Amyloid A (SAA), Beta-2 microglobulin, TNF-Alpha

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