Institute of Immunology Anti-Human RIG-I Monoclonal Antibody

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About RIG-I

RIG-I (retinoic acid inducible gene-I) is an RNA helicase in the cytoplasm, a protein molecule with a total length of 925aa and approximately 116kDa. There are two CARD (caspase recruitment domains) on the N-terminal, and there is a CTD (c terminal domain) involved in RNA binding on the C-terminal.


RIG-I is a molecule that works in the innate immune system and is known to recognize intracellular RNA such as influenza virus, Sendai virus, and hepatitis virus, and to activate type I interferon genes and inflammatory cytokine genes.


Product List

Catalog # Product Clone Subclass Buffer Mass/Volume
2AIIA01 Monoclonal Antibody Against Human RIG-I N3508 IgG1 Saline 0.1mg/0.2mL
Host
Immunogen
Reactivity
Application
Epitope
Mouse
Purified Recombinant Protein (Full-Length)
Human
WB・Super-Shift Assay・IP・ICC
447-925aa(Recognizes both active&inactive types)



 

 

 

 

 

 

 

 

 

 

 
Reference: Onomoto K, et al: PLoS One. 7(8):e43031, 2012.

Catalog # Product Name Clone Subclass Buffer Mass/Volume
2AIIA02 Monoclonal Antibody Against Human RIG-I N3530 IgG1 Saline 0.1mg/0.2mL
Host
Immunogen
Reactivity
Application
Epitope
Mouse
Purified Recombinant Protein (Full-Length)
Human
WB・Super-Shift Assay・IP・ICC
218-229aa(Recognizes both active&inactive types)



 

 

 

 

 

 

 

 

 

 

 
Reference: Onomoto K, et al: PLoS One. 7(8):e43031, 2012.

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