Fina Biosolutions_Antibody-Dextran Conjugates
Antibody-Dextran Conjugates
Antibody dextran conjugates consists of multiple copies of antibody covalently linked to high molecular weight dextran, creating a highly multivalent antibody construct. These constructs serve to crosslink receptors, which are the antibody target, on cell surfaces.
Crosslinking membrane IgD on B cells with unconjugated anti-IgD antibody induces B cell proliferation at µg/ml concentrations. By contrast, anti-IgD dextran induces vigorous B cell proliferation at ng/ml. Furthermore, in contrast to unconjugated anti-IgD, anti-IgD-dex-activated B cells undergo substantial Ig class switching and differentiation into Ig-secreting cells in the presence of various second signals, including cytokines and Toll-like receptor ligands. Thus, Anti-IgD-dex is an efficient and potent polyclonal B cell activator for studying a wide range of B cell functions.
Fina Biosolutions provides anti-IgD and anti-IgM dextran conjugates, targeting mouse and human.
All antibody dextran conjugates are stored at -°80C and are shipped on dry ice.
Cat. No. | Product | Concentration | Size |
---|---|---|---|
FinaBio#0001 | Anti-IgD dextran (mouse) | 100 ug/ml | 10 ug |
FinaBio#0002 | Anti-IgD dextran(human) | 100 ug/ml | 10 ug |
FinaBio#0003 | Anti-IgM dextran (mouse) | 100 ug/ml | 10 ug |
FinaBio#0004 | Anti-IgM dextran(human) | 100 ug/ml | 10 ug |
FinaBio#0005 | Human IgG dextran | 100 ug/ml | 10 ug |
FinaBio#0006 | Anti-IgD (Fab2) dextran (mouse) | 100 ug/ml | 10 ug |
FinaBio#0007 | Anti-IgD Dextran (rat) | 100 ug/ml | 10 ug |
FinaBio#0008 | Anti-IgG Fc-gamma (human) | 100 ug/ml | 10 ug |
FinaBio#1000A | Custom Dextran Conjugates | – | Inquire |
FinaBio#1000B | Bulk and quantiy orders | – | Inquire |
Please contact us for any inquiries, questions, or information requests.
Tokyo Future Style, Inc.
info@tokyofuturestyle.com
TEL:029-851-9222 FAX:029-851-9220