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Provitro has more than 10 years of experience in commercial cell culture technologies, target validation services and tissue microarrays. With support from the Pathological Institutes in Berlin, they have gathered a sizable biobank covering normal samples to pathological samples such as tumor, inflammatory and degenerative diseases.

 

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➤ FFPE Tissue Microarray 　　・Normal Tissue 　　・Neoplastic (Tumor) Tissue 　　・Inflammatory & Autoimmune Tissue 　　・Cardiovascular Tissue 　　・Internal Control ➤ Custom FFPE Tissue Samples

 

FFPE Tissue Microarray (TMA)

・Ideal tool in standardised high-throughput analysis for antigen distribution or validation of newly identified pathogenic genes
　in multiple tissue samples.
・Requires only a very small (few µl) amount of reagent to analyse dozens or hundreds of tissues, i.e. perfectly applicable to
　screening procedures.
・Suitable for a wide range of analytical techniques, such as histochemical stains, immunological stains with either chromogenic
　or fluorescent visualisation, in situ hybridisation (including both mRNA ISH and FISH) and even for tissue micro-dissection
　techniques.
・Identical treatment of all tissue samples, i.e., reagent concentrations are identical for each case, as are incubation time
　and temperatures, wash conditions, and antigen retrieval, if necessary.
・Sufficient area for morphological evaluation is provided by tissue spots with a diameter of up to 2 mm.
・Efficient utilisation of each archived tissue block by multiplicative needle biopsies without sacrificing the original tissue block.

Normal Tissue Microarray

Number	Product Name	Specifications
401 1110	Normal adult tissue I	30 x 1.5 mm
401 1120	Normal adult tissue II	70 x 2.0 mm
401 1130	FDA recommended normal tissue panel	132 x 1.5 mm
401 1210	Normal adult brain tissue	9 x 1.5 mm
401 1211	Normal adult and fetal bone tissue	20 x 2.0 mm
401 1221	Normal adult cartilage tissue I	20 x 2.0 mm
401 1222	Normal embryonic and fetal cartilage tissue II	20 x 2.0 mm
401 1223	Normal adult and neonatal cartilage tissue	40 x 2.0 mm
401 1310	Normal tissue, multi-species	48 x 1.5 mm
401 1401	Stem cell rich tissue	18 x 2.0 mm

 

 
Neoplastic (Tumor) Tissue Microarray

Number	Product Name	Specifications
401 2101	Lymphoma	20 x 2.0 mm
401 2201	Colon carcinoma	60 x 1.5 mm
401 2202	Mamma carcinoma	59 x 1.5 mm
401 2203	Cervical carcinoma	52 x 2.0 mm
401 2204	Lung carcinoma	54 x 1.5 mm & 6 x 2.0 mm
401 2205	Thyroid tumor, matched normal tissue and Morbus Basedow	101 x 1.5 mm
401 2206	Pancreas tumor, matched normal tissue and pancreatitis	96 x 1.5 mm
401 2207	Esophagus cancer	63 x 2.0 mm
401 2208	Cholangiocarcinoma, matched lymph node metastasis and matched normal liver	86 x 2.0 mm
401 2209	Prostate tumor, matched prostatic intraepithelial neoplasia (PIN) and normal tissue	77 x 1.5 mm
401 2210	Endometrium	60 x 2.0 mm
401 2211	Colon-UICC	71 x 2.0 mm
401 2212	Skeletal tumors	54 x 2.0 mm
401 2213	Ovarian carcinoma	75 x 1.5 mm
401 2401	Multitumor – 4 organs	12 x 2.0 mm
401 2402	Multitumor – 10 organs	22 x 2.0 mm
401 2403	Multitumor – 12 organs	24 x 2.0 mm

 

 
Inflammatory and Autoimmune Tissue

Number	Product Name	Specifications
401 3101	Colitis	(36+1) x 2.0 mm
401 3201	Synovitis	28 x 2.0 mm
401 3301	Autoimmune	43 x 2.0 mm

 

 
Cardiovascular Tissue

Number	Product Name	Specifications
401 4101	Myocardial infarction	50 x 2.0 mm
401 4102	Myocardial hypertrophy I – left heart	22 x 2.0 mm
401 4103	Myocardial hypertrophy II – right heart	22 x 2.0 mm
401 4201	Vascular tissue	50 x 2.0 mm

 

 
Internal Control

Number	Product Name	Specifications
401 5101	Antibody control TMA – Her2	2 x 1.5 mm
401 5201	Antibody control TMA – Her2	4 x 1.5 mm
401 5102	Antibody control TMA – CK7	2 x 2.0 mm
401 5103	Antibody control TMA – BCL2	2 x 2.0 mm
401 5104	Antibody control TMA – CD20	2 x 2.0 mm
401 5105	Antibody control TMA – CD117 (c-kit)	2 x 1.5 mm
401 5106	Antibody control TMA – S100	2 x 1.5 mm
401 5107	Antibody control TMA – p16	2 x 1.5 mm
401 5108	Antibody control TMA – p53	2 x 1.5 mm
401 5109	Antibody control TMA – p63	2 x 1.5 mm
401 5110	Antibody control TMA – ER	2 x 2.0 mm
401 5111	Antibody control TMA – PgR	2 x 1.5 mm
401 5112	Antibody control TMA – CK20	2 x 1.5 mm
401 5113	Antibody control TMA – CK5/6	2 x 1.5 mm
401 5114	Antibody control TMA – FLI	2 x 1.5 mm
401 5115	Antibody control TMA – actin	2 x 1.5 mm
401 5116	Antibody control TMA – PSA	2 x 1.5 mm
401 5117	Antibody control TMA – EGFR	2 x 1.5 mm
401 5118	Antibody control TMA – CK18	2 x 1.5 mm
401 5119	Antibody control TMA – CK17	2 x 1.5 mm
401 5120	Antibody control TMA – CK14	2 x 1.5 mm
401 5121	Antibody control TMA – CK8	2 x 1.5 mm
401 5222	Antibody control TMA – MUC1	4 x 1.5 mm
401 5223	Antibody control TMA – Ki67	4 x 1.5 mm
401 5224	Antibody control TMA – survivin	4 x 1.5 mm
401 5225	Antibody control TMA – W6/32	4 x 1.5 mm
401 5126	Antibody control TMA – Dog-1	2 x 2.0 mm
401 5127	Antibody control TMA – CD3	2 x 1.5 mm
401 5128	Antibody control TMA – CD30	2 x 1.5 mm

 

Custom FFPE Tissue Samples(Block/Slide/Microarray)

Besides the tissue microarrays listed in the catalog, provitro can also search and provide tissue samples from its biobank that meets your requirements for FFPE blocks, slides, and microarrays.

Example Criteria

Donor	Age/Gender/etc.
Tissue	Connective Tissue/Colon/Stomach/Skin/Lymph Node/Mamma/Rectum/Larynx/Pancreas/Gallbladder/Liver/etc.
Diagnostic	Normal/Tumor(Adenocarcinoma/Squamous Cell Carcinoma/Basal Cell Carcinoma/etc.)/Inflammatory/etc.