Clinical Samples|Tokyo Future Style, Inc.

Clinical samples (Human specimens)

Normal specimens ( Sera / Plasma / whole blood / Urine / CSF)
Bulk Sera
Correlation Specimens( Sera / Plasma)
Custom Collections
Clinical Specimens (Sera / Plasma / Urine / CSF)

About the listed specimens

All specimens are human originated samples which were (or will be) collected with informed consent to the donors under IRB regulations. We will attach the certificate of IRB by the name of Authorized suppliers.
About normal specimens, all of our specimens are confirmed “Negative” for the following viral markers by the FDA approved methods.

HIV RNA, HCV RNA, Syphilis, anti-HIV 1/2, anti-HCV, HBsAg, and anti-HTLV1/2 by US FDA approved methods.

About the other specimens than normal specimens, by their characteristic, some are viral tested, but others are not viral tested. Please confirm in each case.
For Correlation Specimens, the assay method and the name of the IVD are attached.
For Clinical Specimens, the situation of patients, e.g. disease stage, medication, diagnostic test result etc. are attached.

※These specimens are RUO material.
It is not allowed to use as IVD and/or to apply to human bodies.

Normal specimens ( Sera / Plasma / Whole blood / Urine / CSF)

Single donors / Pool samples
Filtered/Unfiltered
Anticoagulant for Plasma / Whole blood : K3 EDTA, Lithium Heparin, Sodium Citrate and so on.
Fresh frozen on request

Feature of our specimens

We can search the proper specimens based on the customer’s requests among tens of thousands of samples in our network in USA and Eurpe.
We can meet various requests from 1ml to dozens of litters, single donors or pool samples.
It is possible to make the panels by generation, age and so on.
We can meet various requests, for example, to test the various markers using the commercially available IVD, body measurement, interviewing disease history, medication, living habit and so on at the time of blood collection.

About normal specimens, all of our specimens are confirmed “Negative” for the following viral markers by the FDA approved methods.

HIV RNA, HCV RNA, Syphilis, anti-HIV 1/2, anti-HCV, HBsAg, and anti-HTLV1/2 by US FDA approved methods.

Correlation Specimens( Sera / Plasma)

Abused Drugs	Acetaminophen Amphetamines Barbiturates Benzodiazepine Cannabinoids Ethanol Methadone Methamphetamines Opiates Phencyclidine Propoxyphene Salicylate Tricyclic Antidepressants
Congenital Disorders	CMV IgG/IgM Rubella IgG/IgM Toxo IgG/IgM
Diabetes	Insulin Glycated HbA1c
Anemia	B-12 Ferritin Folate
Autoimmune	RF ANA dsDNA ssDNA SSA SSB Scl-70 Jo-1
Heart Disease	CK-MB Myoglobin Troponin I Homocysteine
Cancer	AFP CA 125 CA 15-3 CA 19-9 CEA CA 27-29 CA 72-4 Cyfra HER2 Nu NSE PAP Free PSA Total PSA
General Chemistries	Albumin ALT Alkaline Phosphate AST CEA CA 27-29 Amylase Bilirubin Calcium Chloride Cholesterol Creatinine CK GGT Glucose HDL IgA IgG IgM LDL Lipase Magnesium Phosphorus Potassium Protein Sodium Triglyceride Uric Acid UIBC
Hepatitis/HIV	HIV 1/2 Ab HIV Ag HIV PCR/HIV bDNA HBsAg, HBeAg, HBclgM Anti-HBc, Anti-HBs, Anti-HBe HBV DNA Anti-HCV HCV PCR/HCV bDNA HAV IgG/HAV IgM HTLV 1/2
Therapeutic Drug Monitoring	Carbamazepine Cortisol Digoxin Gentamicin Phenobarbital Phenytoin Procainamide Quinidine Theophylline Tobramycin Valproic Acid Vancomycin
Thyroid/Endocronology	ACTH TSH Total T3 Total T4 T Uptake Free T4 TPG Anti-TPO Anti-TG
Other	H.Pylori Cyclosporine FK-506 FLM Methotrexate Random Hospital pecimens

For Correlation Specimens, the assay method and the name of the IVD are attached.

※These specimens are RUO material.
It is not allowed to use as IVD and/or to apply to human bodies.

Clinical Specimens (Sera / Plasma / Urine / CSF)

Hepatitis B Virus	Chronic infection Acute Infection HBV Recovered HBV Viral Load HBV Vaccine Panels Patients at Risk of Transmitting Hepatitis B
Hepatitis C Virus	Chronic Infections Acute Infections HCV Viral Load Longitudinal Collections Patients at Risk of Transmitting Hepatitis C
HIV/AIDS	CDC Defined Late Stage Patients Asymptomatic Retroviral Naive Patients Pre/Post Anti-Viral Treatments HIV Viral Load Patients at Risk of Transmitting HIV
OB/GYN	Polycystic Ovary Syndrome Endometriosis Pregnancy, Trimester Specific Menstrual Cycle Panels Pre/Post Menopausal
Autoimmune	Rheumatoid Arthritis Autoimmune Hepatitis Systemic Lupus Scleroderma Osteoporosis Sjogrens Syndrome
Oncology	Ovarian Cancer Breast Cancer Colorectal Cancer Prostate Cancer Lung Cancer Small Cell Lung Liver Cancer Kidney Cancer Skin Cancer
Cardiovascular	Hypertensive Hyperlipidemia Myocardial Infarctions Congestive Heart Failure
Miscellaneous	IV Drug Abusers Men Sex Men (MSM) High Risk Behavior Sexually Transmitted Diseases Alcoholic Cirrhosis Hemophiliacs Dialysis Multiple Sex Partners Transplant Recipients Elevated Lipids

For Clinical Specimens, the situation of patients, e.g. disease stage, medication, diagnostic test result etc. are attached.

※These specimens are RUO material.
It is not allowed to use as IVD and/or to apply to human bodies.

Bulk Sera

HIV	PCR Quantified bDNA Quantified Anti-HIV 1/2 HIV-Ag HIV Western Blot HIV False Positive
HCV	PCR Quantified bDNA Quantified HCV Genotyped Anti-HCV HCV RIBA Profiled RIBA 2.0 Ind/3.0 Pos. HCV Ag HCV False Reactive
Other Bulk Sera	Autoimmune Disease HTLV 1/2 Confirmed Syphilis Confirmed Reactive Toxo IgG/IgM Rubella IgG/IgM CMV IgG/IgM Lyme IgG/IgM TP Positive HSV 1/2 IgG/IgM Tumor Marker Post Menopausal Whole Blood Platelets Expired Red Blood Cells Urine
Interference Specimens	Elevated Rheumatoid Factor Elevated Triglyceride Elevated Cholesterol Elevated ALT Lipemic Icteric Hemolyzed HAMA Positive Third Trimester Pregnancy ANA Positive Multiple Myeloma Multiparous Females
HBV	HBV Neutralized HBsAg Reactive HBV PCR Qualitative Anti-HBc Anti-HBc IgM HBeAg/Anti-HBe HBsAg False Reactive HBV Subtype ad or ay

※These specimens are RUO material.
It is not allowed to use as IVD and/or to apply to human bodies.

Custom Collections

Prospective collection of various specimens according to the customer’s projects.
( 2 Weeks to 2 month based on the requested sample type, volume etc.)

Anti-Coagulant Studies	Matched sets from single subjects Normal and infectious subjects Custom (Handling per your specifications)
Subject Contracting	Special collections from uniquesubjects Based on a physician’s diagnosis Defined inclusion/exclusion criteria Serum, plasma, or whole blood Normal and disease-state subjects
RNA Collections	HIV/HCV/HBV/Normals Volumes up to 250 mL per collection Anti-Viral medication specific PCR/bDNA Quantified HCV Genotyping EDTA, Serum, ACD, CPD, Heparin, Citrate
Stability Studies	HIV/HCV/HBV/Normals Matched Sets and Collection Tube Studies (i.e. Serum, EDTA, PPT, ACD, CPD, Heparin, Citrate) Freeze Thaw Analysis PCR or bDNA Quantified Genomic Collections
Tissue Collections	Paraffin Embedded, OCT, or Frozen Specimens Oncology, Gynecology, Endocrine, Neurological, and Infectious Disease Matched serum available
Vaccine Studies	Flu Lyme Hepatitis A and B

Custom Tissue Collections

Prospective collection of various specimens according to the customer’s projects.
( 2 Weeks to 2 month based on the requested sample type, volume etc.)
Specimens can be supplied by various format such as frozen tissue, FFPE blocks / slides and so on.

Adenoid
Adipose
Adrenal
Anal Sphincter
Aorta
Artery
Bladder
Blood
Bone
Bone Marrow
Brain
Breast
Bronchus
Cartilage
Cervix
Colon
Esophagus
Eye

Fallopian Tubes
Gall Bladder
Gum
Heart
Intestine
Kidney
Larynx
Lip
Liver
Lung
Lymph node
Mouth
Muscle
Navel
Nerve
Omentum
Ovary
Pancreas

Paranasal Area
Parathyroid
Parotid
Penis
Peritoneum
Pharynx
Pituitary
Placenta
Prostate
Rectum
Salivary Gland
Serum
Skeletal Muscle
Skin
Small Intestine
Smooth Muscle
Soft Tissue
Spinal Cord

Spleen
Stomach
Submandibular Gland
Synovium
Testis
Thalamus
Thorax
Thymus
Thyroid
Tongue
Tonsil
Trachea
Ureter
Urethra
Uterus
Vagina
Vein
Vulva

※These specimens are RUO material.
It is not allowed to use as IVD and/or to apply to human bodies.

Please contact us for your any inquiries, questions and information requests.
Tokyo Future Style, Inc.
info@tokyofuturestyle.com
TEL:+81-29-851-9222　FAX:+81-29-851-9220